http://www.buzzerbeater.com/match/42845453/boxscore.aspx
This was my game where I used inside ISO, against a much better team. My PF went 3-11 3 shots were jumpers, my 1 center had solid shooting, the other, shot two 3s, (hit 1), and a lot of jumpers.
meanwhile my PG and SG, kept trying to drive the ball in, or hawk a 3... no middle ground.
Going off OP's logic, yeah, my Cs and PF, should have taken the 18+ shots, and tried to dominate inside. But I believe its not so much, isolating players inside, as the players inside position themselves in such a way that perimeter players get a 1on1 to drive or shoot or pass?