This season in Italy there is a II vs. II and at least 4 II vs. III games in the first cup round.On the other hand it is quite common to have bots still in the 4th-5th round.My suggestion is to forbid bot vs. bot games, so that the big majority of them won't reach the second round and the competition will be fairer for everybody :)
there should be "pools"
Again, how it is "totally unfair"?
If the cup was seeded (a horrible idea IMO) then you could theoretically eliminate the bots earlier if all humans were seeded first.
But isnt the idea of the cup that it can be a fairytale journey for some teams and an abrupt shortlived romance for others?