I remember reading about different offenses/defenses & the stamina effect a long while ago. There was a *slight* effect from something like Run & Gun, but really only Full Court Press has a major impact.
It's not worth running a worse offense/def. for your team, only for whatever small effect it has on your opponent's stamina. (FCP excluded). Especially just on a single player's. But if you face a team that plays most or all of it's starters close to all 48 min & has zero depth... That's when tiring them out can really be worth it (FCP / RNG)
There's a chance you're right about the 30 min guy, but low minutes doesn't necessarily mean poor stamina. Well unless the backup is complete garbage. A lot of my backups averaged 20-25 min per game last season because i had a deep team. & that's excluding blowout wins.